The role of myosin II RLC function
and regulation
This site is currently under construction. Please refer to the following publications.
Pengxin Chen, Bernard M. Chaudoir, Kathleen M. Trybus and Rex L. Chisholm. 1999. Expression of Chicken gizzard RLC complements the cytokinesis and developmental defects of Dictyostelium RLC null cells. J. Muscle Res. Cell. Motil. 20, 177-186. PDF
Wendy A. Wolf, Teng-Leong Chew and Rex L. Chisholm. 1999. Regulation of cytokinesis. Cell. Mol. Life Sci. 55, 108-120. PDF
Bernard M. Chaudoir, Patricia A. Kowalczyk and Rex L. Chisholm. 1999. Myosin regulatory light chain mutation affect enzyme function and kinetics. J. Cell Sci. 112, 1611-1620. PDF
Guyu Ho and Rex L. Chisholm. 1997. Substitution mutations in the myosin essential light chain lead to reduced actin-activated ATPase activity despite stoichiometric binding to the heavy chain. J. Biol. Chem. 272: 4522-4527. PDF
Guyu Ho, Tung-Ling Chen and Rex L. Chisholm. 1995. Both the Amino and Carboxyl Termini of Dictyostelium Myosin Essential Light Chain Are Required for Binding to Myosin Heavy Chain. J. Biol. Chem. 270, 27977-27981. PDF
Tung-Ling L. Chen, Patricia Kowalczyk, Guyu Ho and Rex L. Chisholm. 1995. Targeted disruption of the Dictyostelium essential myosin light chain produces cells defective in cytokinesis and morphogenesis. J. Cell Sci. 108. 3207-3218. [Abstract]
Bruce D. Ostrow, Pengxin Chen, and Rex L. Chisholm. 1994. Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells. J. Cell Biol. 127, 1945-1955. [Abstract]
Pengxin Chen, Bruce D. Ostrow, Sherrie R. Tafuri and Rex L. Chisholm. 1994. Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. J. Cell Biol. 127, 1933-1944. [Abstract]